Train, coach and bus frequencies are being cut amid a collapse in demand and government advice on avoiding non-essential travel.
Northern Trains said there will be cancellations on a dozen routes on Thursday “as a result of Covid-19”.
The affected routes include Liverpool-Manchester airport, Leeds/Sheffield-Nottingham and Newcastle-Carlisle.
South Western Railway said it is cancelling trains at short notice as, “like most organisations, we’re seeing more staff having to stay at home unwell”.
Great Western Railway has announced its sleeper service between London Paddington and Penzance – known as the Night Riviera will be suspended after Friday “to protect our customers and colleagues”.
Robert Nisbet, director of nations and regions at industry body the Rail Delivery Group, said train companies will operate services to “as many places as possible in line with demand”.
He added that this must be balanced with “ensuring we are able to maintain staffing levels needed”.
The UK’s largest operator of scheduled coach services, National Express, said it will reduce its capacity by 80%.
This means it will be running the equivalent of a Christmas Day timetable every day.
The firm’s bus networks – which operate across the West Midlands and urban services in Coventry and Dundee – have been cut to a typical Sunday service.
This amounts to the removal of around 40% of its bus mileage.